Ending Alzheimer’s Disease

The End of Alzheimer’s, by Dale Bredesen, MD, is finally out. I’ve been waiting for this forever. All the details of his protocol are now available to the public!

This book may save your mind and the minds of your loved ones. Buy it. Read it. Loan it to your doctor. 🙂

Clinical studies using Bredesen’s ReCODE protocol are showing breakthrough results in patients with mild to moderate Alzheimer’s Disease as well as pre-Alzheimer’s. Over 200 patient success stories exist, many are breathtaking. In each case, the disease was well documented before treatment.

Bredesen’s ingenious basic science research on Alzheimer’s Disease has been published in peer-reviewed journals for 28 years, yet strangely his successful clinical protocol papers have received a cold shoulder from the medical establishment.

Is this because Bredesen is going after causes while mainstream medicine is interested only in masking symptoms? No. It may seem that way sometimes, but the truth is much more interesting.

It boils down to a rigid devotion to traditional experimental design which insists that each component of any therapy must be studied separately. Yes, rarely the medical gatekeepers will make an exception and study two medications simultaneously for certain diseases, but the moon has to be just right for such madness.

Historically this monotherapy approach has worked fairly well for diseases with single causes, but it creates a roadblock to clinical research on complex diseases such as Alzheimer’s.

Though the evidence against monotherapy for Alzheimer’s Disease is a billion-dollar wasteland of failed clinical trials, medical authorities cling to their linear way of thinking, blindly following the sacred tradition of scientific fundamentalists throughout history who have uniformly obstructed all major paradigm shifts with their flawed scientific beliefs and assumptions.

In the case of Alzheimer’s Disease, the belief is simple: if you don’t isolate one thing at a time, you’ll never know exactly what that one thing does in isolation.

Brilliant deduction. The assumption, though, is that knowing what each thing does in isolation should always be the ultimate goal of science and medicine.

This is narrow reductionism – dissecting a thing with the mistaken belief that answers can only be found in the parts.

But as Emerson said, “Foolish consistency is the hobgoblin of small minds.” Sometimes the destruction of a forest cannot be prevented by focusing only on the trees.

In medical science, understanding a system as a functioning whole in both disease and health is more central than reductionism to the overall goal, which is saving patients’ lives.

Bredesen’s protocol is doing exactly that, as documented in peer-reviewed journals.

Disease complexity is why monotherapy experimental design has made no significant progress against Alzheimer’s Disease. This is a disease with at least 36 to 50 different “things” that can go wrong in various combinations that cause the mind to fail. The numbers and mixes of partial causes differ from one patient to the next, but three broad categories have emerged: Inflammatory, atrophic and toxic.

All three produce the same pathognomonic plaques and tangles under light microscopy, so pathologists consider Alzheimer’s a single disease, and drug companies target amyloid with their failed monotherapies.

It’s not as simple as they assume.

Clinically testing Bredesen’s therapies for each of the 36 to 50 causal elements in isolation, if it were possible and fundable (which it’s not), would take many decades and result in falsely negative and/or equivocal outcomes. This is because:

1. Each component of Bredesen’s protocol reverses only a small fraction of the 36 to 50 disease-promoting processes, and those processes are not uniformly distributed in the Alzheimer’s population. So any one of them tested in isolation would not likely have enough overall effect to achieve statistical significance. It’s like firing a shotgun one pellet at a time expecting to stop a serial killer in your bedroom. Stupid, right? Bredesen’s total protocol (tailored to each patient with lab tests) is needed to reverse mild to moderate Alzheimer’s Disease.

2. The synergistic effects of therapeutic components are foolishly eliminated by linear monotherapy-biased experimental design. Keep red and green separate and you won’t discover yellow.

Ignoring Bredesen’s work, as the orthodox mainstream currently prefers to do, is the moral equivalent of physical abuse to Alzheimer’s patients.

The mechanisms producing Alzheimer’s Disease take decades to produce symptoms, so when memory loss or difficulty with word-finding shows up, the disease has already been silently progressing for decades. The earlier you treat it, the better your chances for complete reversal. The worst thing you can do is wait for early symptoms to progress.

If you know anyone with subjective cognitive decline or mild to moderate Alzheimer’s disease, do them the biggest favor of their lives. Read Dale Bredesen’s breakthrough book for yourself and share your knowledge. Maybe the person you care about won’t be fooled by the supercilious, confident, sophisticated-sounding monotherapy zombies who feel they must watch their patients die while waiting for a prescription pill from a drug company.

Sorry, that sounds harsh. But people are dying in the worst imaginable hell while a scientifically documented breakthrough is ignored. It’s astonishing!

The problem is that most MD’s are too busy to read extensively and learn how to distinguish good science from unsubstantiated claims. So they blindly listen to authorities who have the power to take away their licenses.

In medical school, we studied our lecture notes and books with virtually no impetus to learn to critically evaluate journal articles. We had one brief class in statistics.

Anyway, here’s a video interview of Dale Bredesen discussing the groundbreaking, unprecedented results of his ReCODE protocol. Enjoy!

Learning the truth is always fun, and…

“It’s fun to have fun, but you’ve got to know how.” – Dr. Seuss.

Morrill Talmage Moorehead, MD
Retired Pathologist, science fiction writer, and novel content editor.

(I have no conflicts of interest to report and no personal acquaintance with Dr. Bredesen.)

31 thoughts on “Ending Alzheimer’s Disease

    • It’s a great read. I recommend reading it with a pen and paper so you can write down anything you might want to act upon. The ketogenic diet and “meditation” have a great deal of science behind them but tend to be shrugged off as insubstantial because of our preconceived ideas. Caveat: make sure your kidney function is normal and you don’t have a tendency to form kidney stones before you try a ketogenic diet/lifestyle. Long story, but I’ll gladly share the details if they’re relevant to your concerns. 🙂

  1. Nice to see a fellow doctor providing quality information to the world that our industry has chosen to minimize (at this time.) I have been watching the 12 part series as well.
    In my opinion, doctors must be the first segment of our population to read this book to spread this message more effectively. Consumers/patients are still too fearful of their physicians to contradict their traditional advice.

    • You’re right. If MD’s reject “functional medicine” as so many seem determined to do, the “alternative” doctors (not sure what the proper term is for them now – “holistic?”) will become the true physicians of tomorrow. We MD’s will be seen as the brainwashed property of drug companies.

      I’ve had undiagnosed hypothyroidism for most of my adult life (missed by several MD’s). It took a young natureopath doc to diagnose it. The only reason I asked him to check it out was because I’d read a popular book on the subject by an MD who didn’t simply look at a high “normal” TSH and move on regardless of symptoms.

      Bredesen is a genius, I think. His clinical work needs to be spread far and wide, and respected as much as his basic research.

      Your article on Sam Clovis is an eye-opener! “He is a radio talk show host that studied political science and business administration in college. He is being considered for the position as Chief Scientist for the U.S. Department of Agriculture.”

      Amazing! Great website you’ve created!

      Cheers,
      Talmage

    • Thank you. Bredesen’s protocol is really working. The more I look into it, the more remarkable the results are. His book is one of the best investments anyone can make for themselves and their loved ones because Alzheimer’s has reached epidemic proportions – we’re all at risk (due to lifestyle issues), not just the people with ApoE4 homozygous and heterozygous genotypes.

      Thanks for stopping by. 🙂

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  3. Any possibilities at controlling this devastating disease are exciting to learn about. My family has been hit hard with Alzheimer’s so I’m always searching for new information. Thanks!

    • Both of my parents had dementia when they died in their 80’s. I’ve always had a bit of difficulty at word finding when I’m talking, even in my 30’s, so I’m going all out to avoid this nightmare. Nothing like an ounce of prevention. 🙂 Thanks for your comment and connection.

      • I’m being very cautious myself as my mother and two of her sisters suffered through the turmoil. Recently, I found out that two of my dad’s sisters also met that same fate. So you can see why I’m concerned. Recently, I was in a car accident and had a concussion. I don’t remember much of what happened for about a five hour period. Know that’s not the same thing, but it showed me how frightening it is not to remember.

  4. Thanks for this posting. Forty years ago, I attended a lecture with coworkers on the oncology unit where I then worked. We heard from an oncologist who ran a clinic just over the border in Mexico. The clinic was having great success with individualized care, the opposite of standardized care, which is still practiced today. A young man and his mother were part of the lecture. As a boy, he’d been told by Mayo that he had astrocytoma and would not live. Mom took him to Mexico, where an individualized protocol got rid of the tumors. Part of his detailed treatment plan involved drinking large amounts of olive oil. The point is that nothing invasive was done and the brain tumors disappeared. This clinic came into being when an American physician insisted that the large dosing practice of chemotherapy was not the answer to cancer. Today, many clinics are marginally trying to employ the same individualized protocols. Here’s hoping Dr. Bredesen’s study doesn’t take as long to put into practice.

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